Risk factors for metachronous gastric carcinoma development after endoscopic resection of gastric dysplasia: Retrospective, single-center study

Table 3 Analysis of clinical factors associated with occurrence of synchronous lesions n (%)

	Control group	Synchronous group	Univariate analysis	Multivariate analysis
	(n = 488)	(n = 80)	P value	OR	95%CI	P value
Sex			0.120
Male	328 (67.2)	61 (76.2)
Female	160 (32.8)	19 (23.8)
Age			0.000			0.000
≥ 60	343 (70.3)	40 (50.0)		0.395	0.241-0.646
< 60	145 (29.7)	40 (50.0)		1.000
Dysplasia			0.500
Low grade	417 (85.5)	66 (82.5)
High grade	71 (14.5)	14 (17.5)
En bloc resection	179 (37.7)	29 (36.2)	0.941
Intestinal metaplasia	155 (31.8)	42 (52.5)	0.001	2.260	1.377-3.707	0.001
Atrophy			0.044			0.086
Closed	445 (91.2)	67 (83.8)		1.000
Open	43 (8.8)	13 (16.2)		1.860	0.915-3.783
Resection method			0.269
EMR	359 (73.6)	64 (80.0)
ESD	129 (26.4)	16 (20.0)
Endoscopic findings			0.231
Elevated	326 (66.8)	54 (67.5)
Flat	96 (19.7)	20 (25.0)
Depressed	66 (13.5)	6 (7.5)
Location			0.185
Lower	324 (66.4)	46 (57.5)
Mid	156 (32.0)	31 (38.8)
Upper	8 (1.6)	3 (3.8)
Size			0.295
≤ 3	334 (68.4)	60 (75.0)
> 3	154 (31.6)	20 (25.0)
Helicobacter Pylori infection	385 (78.9)	67 (83.8)	0.371