Intestinal anti-inflammatory activity of Ground Cherry (Physalis angulata L.) standardized CO2 phytopharmaceutical preparation

doi:10.3748/wjg.v23.i24.4369

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jun 28, 2017; 23(24): 4369-4380
Published online Jun 28, 2017. doi: 10.3748/wjg.v23.i24.4369

Table 3 Effects of the PACO₂ standardized extract (25, 50 or 100 mg/kg) on glutathione content, myeloperoxidase and alkaline phosphatase activities in acute phase response of intestinal inflammation induced by trinitrobenzenesulphonic acid

Group	GSH, nmol/g tissue	MPO, U/g tissue	ALP, mU/mg protein
Non-colitic	1687 ± 54.2^a	104 ± 13.7^a	8.91 ± 2.17^a
TNBS control	1295 ± 60	1703 ± 390	28.9 ± 3.07
PACO₂, 25 mg/kg	1208 ± 33.8	1360 ± 286	21.0 ± 2.44
PACO₂, 50 mg/kg	1350 ± 85.1	921 ± 181	18.0 ± 1.62^c
PACO₂, 100 mg/kg	1428 ± 50.6	831 ± 108^c	19.5 ± 1.50^c

Data are expressed as mean ± standard error of the mean.

^cP ≤ 0.05 and

^aP ≤ 0.01. GSH: Glutathione; MPO: Myeloperoxidase; ALP: Alkaline phosphatase.

Citation: Almeida Junior LD, Quaglio AEV, de Almeida Costa CAR, Di Stasi LC. Intestinal anti-inflammatory activity of Ground Cherry (Physalis angulata L.) standardized CO₂ phytopharmaceutical preparation. World J Gastroenterol 2017; 23(24): 4369-4380
URL: https://www.wjgnet.com/1007-9327/full/v23/i24/4369.htm
DOI: https://dx.doi.org/10.3748/wjg.v23.i24.4369