Relevance of proteolysis and proteasome activation in fatty liver graft preservation: An Institut Georges Lopez-1 vs University of Wisconsin appraisal

doi:10.3748/wjg.v23.i23.4211

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jun 21, 2017; 23(23): 4211-4221
Published online Jun 21, 2017. doi: 10.3748/wjg.v23.i23.4211

Table 1 ALT and AST (Liver injury) and GLDH (mitochondrial damage) in steatotic liver grafts preserved in University of Wisconsin and Institut Georges Lopez-1 solutions and then subjected to two hours of normothermic reperfusion

Liver injury	Cont2	UW	IGL-1
ALT, U/L	26.76 ± 4.095	172.1 ± 10.81^a	92.99 ± 8.64^a^c
AST, U/L	24.92 ± 2.42	280.93 ± 14.14^a	202.24 ± 24.71^a^c
GLDH, U/L	26.13 ± 6.83	425.22 ± 156.92^a	143 ± 31.16^a^c

^aP < 0.05 vs Cont,

^cP < 0.05 vs UW. UW: University of Wisconsin; IGL-1: Institut Georges Lopez-1.

Citation: Zaouali MA, Panisello-Roselló A, Lopez A, Castro Benítez C, Folch-Puy E, García-Gil A, Carbonell T, Adam R, Roselló-Catafau J. Relevance of proteolysis and proteasome activation in fatty liver graft preservation: An Institut Georges Lopez-1 vs University of Wisconsin appraisal. World J Gastroenterol 2017; 23(23): 4211-4221
URL: https://www.wjgnet.com/1007-9327/full/v23/i23/4211.htm
DOI: https://dx.doi.org/10.3748/wjg.v23.i23.4211