Antioxidant dietary approach in treatment of fatty liver: New insights and updates

doi:10.3748/wjg.v23.i23.4146

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jun 21, 2017; 23(23): 4146-4157
Published online Jun 21, 2017. doi: 10.3748/wjg.v23.i23.4146

Table 1 Described effects of bioactive compounds on mitochondria

Compound	Effect
Polyphenols
Resveratrol	↑Mitochondrial biogenesis
Resveratrol	↑Complex I activity
Quercetin	↑mtDNA
Quercetin	↑Respiratory chain proteins
Coumestrol	↑Mitochondria number
	↑Respiratory chain proteins
	↑Mitochondrial function
Anthocyanins	↑Fatty acid oxidation
Anthocyanins	↑Compex I activity
Epigallocatechin gallate	↑Fatty acid oxidation
Epigallocatechin gallate	↑Energy expenditure
Curcumin	↑Fatty acid oxidation
Curcumin	↑Respiratory complexes activity
Carotenoids
Lycopene	↓Activation of mPTP
Astaxanthin	↑Fatty acid oxidation
	↑Mitochondrial membrane potential
	↑Respiration efficiency
Fucoxanthin	↑Fatty acid oxidation
Glucosinolates
Glucoraphanin	↓FAD levels
Sinigrin	↑Mitochondrial membrane potential
	↑Respiration efficiency
	↑DNA content

mtDNA: Mitochondrial DNA; mPTP: Mitochondrial permeability transition pore.

Citation: Ferramosca A, Di Giacomo M, Zara V. Antioxidant dietary approach in treatment of fatty liver: New insights and updates. World J Gastroenterol 2017; 23(23): 4146-4157
URL: https://www.wjgnet.com/1007-9327/full/v23/i23/4146.htm
DOI: https://dx.doi.org/10.3748/wjg.v23.i23.4146