Association of keratin 8/18 variants with non-alcoholic fatty liver disease and insulin resistance in Chinese patients: A case-control study

Table 1 Demographics and clinical information of non-alcoholic fatty liver disease patients and controls

	Controls (n = 173)	NAFLD patients (n = 200)	P value
Sex (male, %)	130 (75.14)	164 (82.00)	0.107
Age (yr)	39.55 ± 9.92	40.85 ± 9.89	0.101
ALT (U/L)	21.65 ± 12.69	43.63 ± 29.16	< 0.0001
AST (U/L)	24.74 ± 6.52	33.85 ± 12.93	< 0.0001
FBG (mmol/L)	4.89 ± 0.62	5.40 ± 1.45	< 0.0001
TC (mmol/L)	4.71 ± 0.77	5.68 ± 1.09	< 0.0001
TG (mmol/L)	1.29 ± 0.99	2.86 ± 2.14	< 0.0001
HDL (mmol/L)	1.22 ± 0.29	1.07 ± 0.23	< 0.0001
LDL (mmol/L)	2.80 ± 0.61	3.32 ± 0.95	< 0.0001
UA (μmol/L)	331.33 ± 88.61	412.42 ± 96.60	< 0.0001

Data are presented as mean ± SD. ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; FBG: Fasting blood glucose; TC: Total cholesterol; TG: Triglyceride; HDL: High-density lipoprotein; LDL: Low-density lipoprotein; NAFLD: Non-alcoholic fatty liver disease.