Diabetes recurrence after metabolic surgeries correlates with re-impaired insulin sensitivity rather than beta-cell function

Figure 2 Homeostatic model assessment of insulin resistance of rats at baseline, 4 and 12 wk after operations. ^aP < 0.05 vs Sham group at 4 wk postoperatively; ^cP < 0.05 vs Sham group at 12 wk postoperatively; ^eP < 0.05 vs SG-HFD group at 4 wk postoperatively; ^gP < 0.05 vs DJB-HFD group at 4 wk postoperatively; ⁱP < 0.05 vs SG-LFD at 12 wk postoperatively; ^kP < 0.05 vs DJB-LFD at 12 wk postoperatively. HOMA-IR: Homeostatic model assessment of insulin resistance; SG: Sleeve gastrectomy; SG-LFD: SG rats with common low-fat diet; SG-HFD: SG with high-fat diet; DJB: Duodenal-jejunal bypass; DJB-LFD: DJB rats with LFD; DJB-HFD: DJB rats with HFD.