©The Author(s) 2017.
World J Gastroenterol. May 7, 2017; 23(17): 3122-3132
Published online May 7, 2017. doi: 10.3748/wjg.v23.i17.3122
Published online May 7, 2017. doi: 10.3748/wjg.v23.i17.3122
Table 2 Clinicopathological characteristics of the 81 hepatocellular carcinoma patients with portal/hepatic vein tumor thrombosis, n (%)
| NLR ≤ 2.9 (n = 51) | NLR > 2.9 (n = 30) | P value | |
| Age in years | 48.49 ± 1.52 | 48.47 ± 2.28 | 0.993 |
| Gender | 0.292 | ||
| Male | 48 (94.1) | 30 (100.0) | |
| Female | 3 (5.9) | 0 (0.0) | |
| HBsAg status | 0.281 | ||
| Negative | 3 (5.9) | 0 (0.0) | |
| Positive | 45 (88.2) | 30 (100.0) | |
| Unknown | 3 (5.9) | 0 (0.0) | |
| Preoperative HBV DNA | 0.025 | ||
| < 1 × 103 | 19 (37.3) | 4 (13.3) | |
| ≥ 1 × 103 | 23 (45.1) | 19 (63.3) | |
| Unknown | 9 (17.6) | 7 (23.3) | |
| Preoperative AFP level | 0.038 | ||
| < 400 ng/mL | 19 (37.3) | 5 (16.7) | |
| ≥ 400 ng/mL | 30 (58.8) | 25 (83.3) | |
| Unknown | 2 (3.9) | 0 (0.0) | |
| Preoperative ALT level (U/L) | 41 (10-713) | 42.5 (21-146.5) | 0.697 |
| Preoperative Hgb level (g/L) | 147.79 ± 2.43 | 148.52 ± 4.37 | 0.884 |
| Preoperative PLT level (109/L) | 185.84 ± 12.73 | 201.97 ± 13.97 | 0.417 |
| Preoperative Child-Pugh score | 0.017 | ||
| Child A (5) | 21 (41.2) | 7 (23.3) | |
| Child A (6) | 22 (43.1) | 14 (46.7) | |
| Child B (7) | 4 (7.8) | 5 (16.7) | |
| Child B (8) | 1 (2.0) | 2 (6.7) | |
| Child B (9) | 0 (0.0) | 1 (3.3) | |
| Unknown | 3 (5.9) | 1 (3.3) | |
| Preoperative ICGR15 (%) | 6.42 ± 0.79 | 5.37 ± 0.94 | 0.404 |
| Number of tumors | 0.474 | ||
| Solitary | 28 (54.9) | 14 (46.7) | |
| Multiple | 23 (45.1) | 16 (53.3) | |
| Maximum diameter of tumor (cm) | 8.93 ± 0.58 | 11.88 ± 0.80 | 0.003 |
| Uni/bilobular disease | 0.414 | ||
| Unilobular disease | 48 (94.1) | 26 (86.7) | |
| Bilobular disease | 3 (5.9) | 4 (13.3) | |
| Adjacent organ invasion | 0.722 | ||
| Negative | 32 (62.7) | 20 (66.7) | |
| Positive | 19 (37.3) | 10 (33.3) | |
| Operative procedure | 0.215 | ||
| Minor | 45 (88.2) | 23 (76.7) | |
| Major | 6 (11.8) | 7 (23.3) | |
| Total occlusion time of the hepatic inflow (min) | 17.89 ± 1.58 | 18.18 ± 2.53 | 0.918 |
| Total operative time (min) | 168.43 ± 7.19 | 205.00 ± 13.77 | 0.011 |
| Blood loss (mL) | 579.41 ± 61.82 | 891.67 ± 171.61 | 0.095 |
| Blood transfusion (mL) | 0.061 | ||
| No | 33 (64.7) | 13 (43.3) | |
| Yes | 18 (35.3) | 17 (56.7) | |
| Surgical margin | 0.002 | ||
| ≤ 1 cm | 33 (64.7) | 25 (83.3) | |
| > 1 cm | 18 (35.3) | 1 (3.3) | |
| Unknown | 0 (0.0) | 4 (13.3) | |
| Histological grade of tumor cells | 0.958 | ||
| I-II | 19 (37.3) | 11 (36.7) | |
| III-IV | 32 (62.7) | 19 (63.3) | |
| Postoperative complication | 0.792 | ||
| Negative | 42 (82.4) | 24 (80.0) | |
| Positive | 9 (17.6) | 6 (20.0) | |
| Postoperative hospital stay (d) | 11 (8-28) | 11.5 (8-83) | 0.468 |
- Citation: Li SH, Wang QX, Yang ZY, Jiang W, Li C, Sun P, Wei W, Shi M, Guo RP. Prognostic value of the neutrophil-to-lymphocyte ratio for hepatocellular carcinoma patients with portal/hepatic vein tumor thrombosis. World J Gastroenterol 2017; 23(17): 3122-3132
- URL: https://www.wjgnet.com/1007-9327/full/v23/i17/3122.htm
- DOI: https://dx.doi.org/10.3748/wjg.v23.i17.3122