Pancreaticoduodenectomy in patients ≥ 75 years of age: Are there any differences with other age ranges in oncological and surgical outcomes? Results from a tertiary referral center

Table 1 Demographic and clinical data n (%)

Variable	LE	YE	A	P value	Total
Age, median (range)	77 (75-86)	70 (65-74)	57 (18-64)	< 0.001	70 (18-86)
Female	50 (52.1)	46 (47.9)	38 (39.6)	NS	134 (46.5)
BMI (kg/m2) ± SD	24.6 ± 3.6	24.9 ± 3.4	24.5 ± 4.2	NS
Smoking	37 (50.0)	28 (37.5)	17 (23.6)	0.004	82 (28.5)
Diabetes	21 (21.9)	16 (16.7)	22 (22.9)	NS	59 (20.5)
Jaundice	68 (70.8)	66 (68.8)	65 (67.7)	NS	199 (69.1)
CA 19-9 > 37 mU/L (malignancies)	29 (30.2)	37 (38.5)	43 (44.8)	NS	109 (37.8)
ASA score, mean (range)	2 (2-3)	2 (2-4)	2 (1-3)	NS	2 (1-4)
AA-Charlson Score, mean (range)	6 (3-10)	5 (3-9)	4 (0-8)	NS	5 (0-10)
Harvested lymph-nodes, mean	24	26	26	NS
Pre-operative biliary drain	49 (51.0)	53 (55.2)	48 (50.0)	NS	150 (52.1)
Malignant diagnosis	68 (70.8)	67 (69.8)	68 (70.8)	NS	203 (70.4)
N1 status	41 (60.2)	42 (62.6)	42 (61.8)	NS	125 (61.5)
Neoadjuvant therapy, (PDAC)	10 (20.4)	11 (23.0)	10 (18.5)	NS	31 (20.6)
Adjuvant therapy, yes (all malignancies)	34,	29,	29,	NS	92 (45.3)
	n = 57 (68)	n = 45 (65)	= 45 (64.4)	NS	147 (70.3)

A: Adults; YE: Young elderly; LE: Late elderly; BMI: Body mass index; PDAC: Pancreatic cancer.