In vitro and in vivo antioxidative and hepatoprotective activity of aqueous extract of Cortex Dictamni

Figure 4 Effect of Cortex Dictamni aqueous extract on liver index and hepatic markers in CCl₄-induced liver damage in rats. A: Liver index; B: Aspartate aminotransferase; C: Glutamate pyruvate transaminase; D: Alkaline phosphatase; E: Total bilirubin. The values represent the mean ± SD, with n = 6 animals in each sex group. Statistically significant differences are indicated with asterisks. ^aP < 0.05, ^bP < 0.01, vs the control group; ^cP < 0.05, ^dP < 0.01, vs the CCl₄ group. Group I: Control; Group II: Control + CDAE 320 mg/kg; Group III: CCl₄; Group IV: CCl₄ + silymarin 100 mg/kg; Group V: CCl₄ + CDAE 80 mg/kg; Group VI: CCl₄ + CDAE 160 mg/kg; Group VII: CCl₄ + CDAE 320 mg/kg. CDAE: Cortex Dictamni aqueous extract.