Importance of antimicrobial susceptibility testing for the management of eradication in Helicobacter pylori infection

Table 2 Eradication rates achieved with susceptible guided therapy as first treatment and rescue treatment

Line of therapy	Ref.	Type of therapy	Patients (n)	Methods	Tailored therapy eradication rates
					ITT %	PP %
First Line	Liu et al[83], 2015	RpzBAC, RpzBAF	89	Real-time PCR	98 in RpzBAC group	100 in RpzBAC group
					92.6 in RpzBAF group	94 in RpzBAF group
First Line	Sugimoto et al[90], 2014	RpzAC, RpzAM	153	PCR	96.7 (overall)	97.4 (overall)
Third line	Liou et al[89], 2013	Sequential triple	135	PCR and Agar dilution	80.7	82.6
Fourth	Fiorini et al[91], 2013	Triple (EAC, EAR)	236	E-test	NR	90 in EAC
						88.6 in EAR

B: Bismuth potassium citrate; Rpz: Rabeprazole; A: Amoxicillin; C: Clarithromycin; F: Furazolidone; M: Metronidazole; R: Rifabutin; E: Esomeprazole; NR: Not reported.