High throughput RNA sequencing utility for diagnosis and prognosis in colon diseases

doi:10.3748/wjg.v23.i16.2819

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 28, 2017; 23(16): 2819-2825
Published online Apr 28, 2017. doi: 10.3748/wjg.v23.i16.2819

Table 1 RNA markers in colorectal cancer and ulcerative colitis

Name	Level	Disease	Biomarker	Ref.
miR-143	↓	CRC	Diagnosis	[32]
miR-20a	↑	CRC	Diagnosis, prognosis	[33,37]
miR-21	↑	CRC	Diagnosis	[35]
miR-132	↓	CRC	Prognosis	[36]
DANCR	↑	CRC	Prognosis	[38]
miR-4299	↑	CRC	Chemoresistance	[39]
miR-196b	↓	CRC	Chemoresistance	[39]
miR-214	↑	Active UC and CAC	Diagnosis, prognosis	[40]

The expression levels of several microRNAs are altered in colorectal disease, specifically colorectal cancer and inflammatory bowel disease compared to non-disease states. These microRNAs have been shown to be biomarkers for several disease characteristics. CRC: Colorectal cancer; UC: Ulcerative colitis.

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Citation: Gao M, Zhong A, Patel N, Alur C, Vyas D. High throughput RNA sequencing utility for diagnosis and prognosis in colon diseases. World J Gastroenterol 2017; 23(16): 2819-2825
URL: https://www.wjgnet.com/1007-9327/full/v23/i16/2819.htm
DOI: https://dx.doi.org/10.3748/wjg.v23.i16.2819

Gao M, Zhong A, Patel N, Alur C, Vyas D. High throughput RNA sequencing utility for diagnosis and prognosis in colon diseases. World J Gastroenterol 2017; 23(16): 2819-2825 [PMID: 28522900 DOI: 10.3748/wjg.v23.i16.2819]

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