What is the quantitative risk of gastric cancer in the first-degree relatives of patients? A meta-analysis

Table 1 Characteristics of included studies

Ref.	Year	Country	Controls	Type of outcome	Family history	Quality score (0-9)
Bakir et al[11,12]	2000	Turkey	HB, NC, NGC	Primary	1st	4
	2003
Brenner et al[25]	2000	Germany	HB, NGC	Primary	1st	5
Chen et al[26]	2004	Taiwan	HB, NC, GC, NGI	Primary	1st	6
Chirinos et al[27]	2012	Peru	HB, NC	Primary	Unclear	5
Chow et al[28]	1999	Poland	CB, Healthy	Secondary	Unclear	7
Chung et al[29]	2010	South Korea	HB, NGC	Primary	1st	5
Dhillon et al[30]	2001	United States	PB, Healthy	Primary	1st	7
Ennishi et al[31]	2011	Japan	HB, NGC	Secondary	1st	6
Eto et al[32]	2006	Japan	HB, NGC	Primary	1st	4
Foschi et al[33]	2008	Italy	HB, NC	Primary	1st	6
Gajalakshmi et al[34]	1996	India	HB, NGC	Secondary	Unclear	5
Garcia-Gonzalez et al[35]	2012	Spain	CB, NGI	Secondary	1st	6
Gong et al[36]	2013	South Korea	HB, NGC	Primary	1st	5
García-González et al[37]	2007	Spain	HB, NC, NGC	Secondary	1st/2nd	6
Hong et al[38]	2006	South Korea	HB, NC, NGC	Secondary	1st	4
Huang et al[39]	1999	Japan	HP, NGC	Secondary	1st	5
Ikeguchi et al[40]	2001	Japan	HB, NC, NGC, NGI	Primary	1st-3rd	4
La Vecchia et al[41]	1992	Italy	HB, NC, NGC, NGI	Primary	1st	3
Lee et al[42]	2009	South Korea	HB, NGC	Primary	Unclear	5
Li et al[43]	2010	China	HB, NGI	Secondary	1st	6
Mao et al[44]	2011	China	HB, NGC	Secondary	1st	5
Minami et al[45]	2003	Japan	HP, NC, NGC	Secondary	1st	5
Nagase et al[46]	1996	Japan	HB, NC, NGC	Primary	1st	5
Palli et al[47]	1994	Italy	CB, healthy	Primary	1st	6
Presson et al[13]	2009	Sweden	HB, CB, NC	Secondary	1st/2nd	7
Safaee et al[48]	2011	Iran	HB, Healthy	Primary	1st	6
Shen et al[49]	2009	China	HB, NGC	Primary	1st	6
Shin et al[50]	2010	South Korea	HB, NGC	Primary	1st	6
Wen et al[51]	2014	China	HB + CB, NGC	Secondary	1st	7
Yi et al[52]	2010	China	HB, NGC	Secondary	1st	5
Zhang et al[53]	2009	China	HB, NC	Secondary	1st	6
Zhang et al[54]	2008	China	HB, NC	Secondary	1st	6

HB: Hospital-based; CB: Community-based; NC: Non-cancer; NGI: Non gastrointestinal disorder; NGC: Non-gastric cancer.