Infection does not increase long-term mortality in patients with acute severe alcoholic hepatitis treated with corticosteroids

Table 2 Univariate analysis of variables at baseline and day 7 of steroid treatment to assess association with day 90 outcome

	Day 90 outcome		P value
	Survivor (n = 49)	Non-survivor (n = 23)
Age (yr)	45	53	0.01
Gender (% male)	73	74	1.00
Sepsis on admission (%)	10	13	0.50
Sepsis at any time (%)	51	48	1.00
Sepsis after steroids (%)	33	30	1.00
CRP (mg/L)	30	40	0.15
Baseline bilirubin (μmol/L)	301	279	0.52
Baseline albumin (g/L)	25	24	0.38
Baseline INR	1.8	2	0.14
Baseline PT (s)	18.6	20.5	0.17
Baseline urea (μmol/L)	3.2	5.5	< 0.01
Baseline creatinine (μmol/L)	90	91	0.93
Baseline WBC (× 109/L)	9	10	0.44
Day 7 bilirubin (μmol/L)	244	254	0.67
Baseline DF	51.1	57.2	0.41
Baseline GAHS	7.8	8.7	0.04
Baseline MELD	21.7	23.7	0.23
Lille score	0.38	0.46	0.38

Continuous variables were compared by Mann-Whitney U test and categorical data by Fisher Exact test. CRP: C-reactive protein; INR: International normalised ratio; PT: Prothrombin time; WBC: White blood count; DF: Discriminant function; GAHS: Glasgow alcoholic hepatitis score; MELD: Model for end-stage liver disease.