Validation of the chinese version of the EORTC QLQ-CR29 in patients with colorectal cancer

Table 4 Known group comparisons: scales and items in the QLQ-C30 and CR29 for clinically distinct groups

	Stoma (n = 56)	No stoma (n = 298)	P value1	KPS ≤ 80(n = 162)	KPS > 80(n = 177)	P value1
CR29 scales
Urinary frequency	6.5 ± 14.5	6.1 ± 13.5	0.856	6.7 ± 12.3	5.8 ± 14.9	0.098
Blood and mucus in stool	18.9 ± 25.9	10.3 ± 16.3	0.160	13.8 ± 19.7	7.3 ± 12.7	0.019
Stool frequency	8.0 ± 13.2	8.4 ± 14.8	0.960	11.2 ± 18.2	5.1 ± 9.6	0.017
Body image	81.7 ± 18.9	88.6 ± 14.7	0.004	87.7 ± 17.7	89.0 ± 11.9	0.589
CR29 single items
Urinary incontinence	7.7 ± 4.2	1.6 ± 7.1	< 0.001	0.8 ± 0.7	4.2 ± 11.1	0.001
Dysuria	7.7 ± 16.8	5.4 ± 12.3	0.444	3.2 ± 11.2	8.0 ± 14.7	< 0.001
Abdominal pain	11.9 ± 21.5	12.0 ± 18.7	0.651	13.5 ± 21.0	9.0 ± 16.1	0.059
Buttock pain	10.7 ± 15.7	5.4 ± 13.2	0.005	2.5 ± 8.8	9.0 ± 16.1	< 0.001
Bloating	16.1 ± 16.8	20.9 ± 21.4	0.183	25.2 ± 23.9	15.0 ± 16.6	< 0.001
Dry mouth	11.9 ± 17.3	7.2 ± 15.1	0.025	6.0 ± 14.4	8.0 ± 15.1	0.170
Hair loss	14.3 ± 18.9	9.6 ± 16.6	0.058	7.7 ± 17.2	11.1 ± 16.2	0.010
Taste	15.5 ± 22.9	23.8 ± 21.7	0.002	26.0 ± 25.0	18.8 ± 18.4	0.015
Anxiety	31.0 ± 31.0	44.6 ± 23.7	< 0.001	52.1 ± 22.6	35.1 ± 24.1	< 0.001
Weight	22.6 ± 21.2	44.6 ± 23.7	0.032	32.3 ± 19.9	21.6 ± 16.8	< 0.001
Flatulence	14.3 ± 17.8	5.0 ± 13.4	< 0.001	4.5 ± 14.6	7.0 ± 13.6	0.012
Fecal incontinence	15.5 ± 20.1	4.4 ± 11.9	< 0.001	2.5 ± 10.2	8.0 ± 15.1	< 0.001
Sore skin	26.2 ± 23.5	3.1 ± 10.1	< 0.001	3.5 ± 12.7	9.7 ± 17.5	< 0.001
Embarrassment	25.0 ± 20.4	2.3 ± 8.4	< 0.001	4.1 ± 12.8	7.1 ± 14.6	0.019
Stoma care problems	/	/	/	18.8 ± 20.8	19.8 ± 25.2	0.941
Sexual interest (men)	74.4 ± 23.5	69.8 ± 25.5	0.333	76.3 ± 22.8	66.0 ± 26.0	0.020
Impotence	9.4 ± 17.0	8.5 ± 20.2	0.364	6.5 ± 19.2	10.7 ± 19.9	0.021
Sexual interest (women)	81.0 ± 17.8	77.1 ± 22.5	0.749	83.7 ± 16.8	71.2 ± 25.0	0.005
Dyspareunia	9.5 ± 16.3	4.3 ± 14.1	0.172	2.7 ± 15.0	6.5 ± 13.4	0.012
QLQ-C30 scales
Physical	85.5 ± 12.4	82.9 ± 16.5	0.335	77.6 ± 18.3	89.4 ± 10.7	< 0.001
Role	84.8 ± 17.2	69.4 ± 20.6	< 0.001	61.7 ± 20.6	81.2 ± 16.4	< 0.001
Emotional	80.5 ± 17.7	74.4 ± 14.0	0.001	69.3 ± 14.4	81.2 ± 11.9	< 0.001
Cognitive	79.5 ± 20.5	80.7 ± 20.0	0.397	75.4 ± 34.9	85.9 ± 14.6	< 0.001
Social	60.0 ± 22.4	45.7 ± 25.5	< 0.001	38.5 ± 24.9	55.7 ± 23.5	< 0.001
Overall quality of life	67.9 ± 21.4	67.8 ± 17.4	0.636	59.5 ± 16.5	76.4 ± 14.4	< 0.001
Fatigue	18.8 ± 18.2	22.8 ± 19.9	0.108	30.5 ± 20.3	13.2 ± 13.8	< 0.001
Nausea and vomiting	11.6 ± 13.8	6.1 ± 14.4	< 0.001	4.7 ± 15.7	8.1 ± 12.5	< 0.001
Pain	13.0 ± 16.6	12.0 ± 17.3	0.427	13.3 ± 19.1	9.4 ± 13.8	0.211

¹Wilcoxon rank sum test.