Copyright
©The Author(s) 2017.
World J Gastroenterol. Mar 14, 2017; 23(10): 1872-1880
Published online Mar 14, 2017. doi: 10.3748/wjg.v23.i10.1872
Published online Mar 14, 2017. doi: 10.3748/wjg.v23.i10.1872
Table 1 Clinical features and metastatic sites n (%)
| Features | Bone metastases | P value | Liver metastases | P value | Lung metastases | P value | Distant lymph nodes | P value | Brain metastases | P value | |||||
| Yes | No | Yes | No | Yes | No | Yes | No | Yes | No | ||||||
| Age (yr) | 0.002 | < 0.0001 | 0.008 | < 0.0001 | 0.636 | ||||||||||
| < 65 | 396 (7.7) | 4724 (92.3) | 3996 (78.0) | 1124 (22.0) | 961 (18.8) | 4159 (81.2) | 569 (11.1) | 4551 (88.9) | 37 (0.7) | 5083 (99.3) | |||||
| ≥ 65 | 514 (6.3) | 7599 (93.7) | 6092 (75.1) | 2021 (24.9) | 1677 (20.7) | 6463 (79.3) | 677 (8.3) | 7436 (91.7) | 53 (0.7) | 8060 (99.3) | |||||
| Race | 0.076 | 0.001 | 0.312 | 0.059 | 0.314 | ||||||||||
| White | 727 (9.6) | 9734 (93.1) | 7974 (76.2) | 2487 (23.8) | 2106 (20.1) | 8355 (79.9) | 1005 (9.6) | 9456 (90.4) | 71 (0.7) | 10390 (99.3) | |||||
| Black | 105 (5.9) | 1661 (94.1) | 1388 (78.6) | 378 (21.4) | 329 (18.6) | 1437 (81.4) | 140 (7.9) | 1626 (92.1) | 16 (0.9) | 1750 (99.1) | |||||
| Others | 928 (93) | 78 (7.0) | 726 (73.0) | 280 (27.0) | 203 (19.0) | 803 (81.0) | 905 (90.0) | 101 (10.0) | 3 (0.2) | 1003 (99.8) | |||||
| Gender | 0.002 | < 0.0001 | 0.020 | 0.028 | 0.770 | ||||||||||
| Male | 636 (7.5) | 6613 (92.5) | 5565 (77.8) | 1584 (22.2) | 1372 (19.2) | 5777 (80.8) | 710 (9.9) | 6439 (90.1) | 50 (0.7) | 7099 (99.3) | |||||
| Female | 374 (6.1) | 5710 (93.9) | 4523 (74.3) | 1561 (25.7) | 1266 (20.8) | 4818 (79.2) | 536 (8.8) | 5548 (91.2) | 40 (0.7) | 6044 (99.3) | |||||
| Location of the primary | 0.001 | 0.084 | < 0.0001 | 0.003 | 0.024 | ||||||||||
| Head | 269 (5.8) | 4387 (94.2) | 3580 (76.9) | 1076 (23.1) | 828 (17.2) | 3828 (82.2) | 480 (10.3) | 4176 (89.7) | 21 (0.5) | 4635 (99.5) | |||||
| Body/tail | 340 (7.2) | 4408 (92.8) | 3638 (76.6) | 1110 (23.4) | 961 (20.2) | 3787 (79.8) | 394 (8.3) | 4354 (91.7) | 33 (0.7) | 4715 (99.3) | |||||
| Unknown | 301 (7.9) | 3528 (92.1) | 2870 (75.0) | 959 (25.0) | 849 (22.2) | 2980 (77.8) | 372 (9.7) | 3457 (90.3) | 36 (0.9) | 3793 (99.1) | |||||
| Marital status | 0.083 | 0.895 | 0.083 | 0.014 | 0.189 | ||||||||||
| Married | 512 (7.1) | 6720 (92.9) | 5510 (76.2) | 1722 (23.8) | 1402 (19.4) | 5830 (80.6) | 722 (10.0) | 6510 (90.0) | 43 (0.6) | 7189 (99.4) | |||||
| Unmarried | 398 (6.6) | 5603 (93.4) | 4578 (76.3) | 1423 (23.7) | 1236 (20.6) | 4765 (79.4) | 524 (8.7) | 5477 (91.3) | 47 (0.8) | 5954 (99.2) | |||||
| T stage | < 0.0001 | < 0.0001 | 0.003 | < 0.0001 | < 0.0001 | ||||||||||
| T1 | 29 (8.9) | 296 (91.1) | 242 (74.5) | 83 (25.5) | 59 (18.2) | 266 (81.8) | 23 (7.1) | 302 (92.9) | 3 (0.9) | 322 (99.1) | |||||
| T2 | 209 (6.7) | 3079 (93.6) | 2705 (82.3) | 583 (17.7) | 595 (18.1) | 2693 (81.9) | 277 (8.4) | 3011 (91.6) | 17 (0.5) | 3271 (99.5) | |||||
| T3 | 200 (5.5) | 3460 (94.5) | 2699 (73.7) | 961 (26.3) | 711 (19.4) | 2949 (80.6) | 345 (9.4) | 3315 (90.6) | 11 (0.3) | 3649 (99.7) | |||||
| T4 | 153 (6.8) | 2106 (93.2) | 1611 (71.3) | 648 (28.7) | 504 (22.3) | 1755 (77.7) | 278 (12.3) | 1981 (87.7) | 13 (0.6) | 2246 (99.4) | |||||
| Tx | 319 (9.0) | 3382 (91.0) | 2831 (76.0) | 870 (24.0) | 769 (20.5) | 2932 (79.5) | 323 (10.0) | 3378 (90.0) | 46 (1.2) | 3655 (98.8) | |||||
| N stage | < 0.0001 | 0.788 | < 0.0001 | < 0.0001 | 0.089 | ||||||||||
| N0 | 395 (5.8) | 6424 (94.2) | 5210 (76.4) | 1609 (23.6) | 1143 (16.8) | 5676 (83.2) | 310 (4.5) | 6509 (95.5) | 36 (0.5) | 6783 (99.5) | |||||
| N1 | 354 (8.7) | 3729 (91.3) | 3097 (75.9) | 986 (24.1) | 1018 (24.9) | 3065 (75.1) | 811 (19.9) | 3272 (80.1) | 34 (0.8) | 4049 (99.2) | |||||
| Nx | 161 (6.9) | 2170 (93.1) | 1781 (76.4) | 550 (23.6) | 477 (20.5) | 1854 (79.5) | 125 (5.4) | 2206 (94.5) | 20 (0.9) | 2311 (99.1) | |||||
| Surgery of the primary | 0.035 | < 0.0001 | 0.006 | 0.265 | 0.422 | ||||||||||
| Yes | 7 (3.1) | 218 (96.9) | 112 (49.8) | 113 (50.2) | 26 (11.6) | 199 (88.4) | 15 (6.7) | 210 (93.3) | 0 (0) | 225 (100.0) | |||||
| No | 903 (7.0) | 12105 (93.0) | 9976 (76.7) | 3033 (23.3) | 2612 (20.1) | 10369 (79.9) | 1231 (9.5) | 11777 (90.5) | 90 (0.7) | 12918 (99.3) | |||||
| Surgery of the metastases | 0.808 | < 0.0001 | 0.002 | < 0.0001 | 0.503 | ||||||||||
| Yes | 38 (6.6) | 534 (93.4) | 288 (50.3) | 284 (49.7) | 81 (14.2) | 491 (85.8) | 91 (15.9) | 481 (84.1) | 6 (1.0) | 566 (99.0) | |||||
| No | 872 (6.7) | 11789 (93.3) | 9800 (77.4) | 2861 (22.6) | 2557 (20.2) | 10104 (79.8) | 1155 (9.1) | 11506 (90.9) | 84 (0.7) | 12577 (99.3) | |||||
- Citation: Oweira H, Petrausch U, Helbling D, Schmidt J, Mannhart M, Mehrabi A, Schöb O, Giryes A, Decker M, Abdel-Rahman O. Prognostic value of site-specific metastases in pancreatic adenocarcinoma: A Surveillance Epidemiology and End Results database analysis. World J Gastroenterol 2017; 23(10): 1872-1880
- URL: https://www.wjgnet.com/1007-9327/full/v23/i10/1872.htm
- DOI: https://dx.doi.org/10.3748/wjg.v23.i10.1872