Sodium butyrate attenuates high-fat diet-induced steatohepatitis in mice by improving gut microbiota and gastrointestinal barrier

Figure 3 Influences of sodium butyrate on gut microbiota at the genus level. A-K: Alistipes, Christensenellaceae_uncultured, Enterorhabdus, Lactobacillus, Parabacteroides, Parasutterella, Rikenella, Ruminococcaceae_incertae_sedis, Ruminococcaceae_unclassified, and Ruminococcaceae_uncultured in the HF group were lower than the control. NaB intervention reversed the changes in Christensenellaceae_uncultured, Parabacteroides, Parasutterella and Lactobacillus. NaB treatment significantly increased Blautia; L: Relative read abundance of different bacterial genera within the different communities. Sequences that could not be classified into any known group were assigned as “norank”. Data represent means ± SEM. ^aP < 0.05, ^bP < 0.01 and ^eP < 0.001.