Trefoil factor-3 is not a useful marker of mucosal healing in Crohn's disease treated with anti-TNF-α antibodies

Table 1 Correlation of Crohn’s disease endoscopic activity assessed by Simple Endoscopic Score for Crohn’s disease with clinical and biochemical parameters recorded at the same time

	Simple endoscopic score for Crohn’s disease vs biochemical parameters
	CDAI	Albumin	WBC	PLT	CRP	Hb	Ferritin	Fibrinogen	ESR
R value	0.66	-0.62	0.3500	0.4400	0.57	-0.40	0.12	0.59	0.57
P value	< 0.0001	< 0.0001	0.0071	0.0005	< 0.0001	0.0018	0.41	< 0.0001	< 0.0001

Endoscopy was performed in 29 patients before and after the induction therapy with anti-TNF-α agents (n = 58). CDAI: Crohn’s Disease Activity Index; WBC: White blood count; PLT: Platelets; CRP: C-reactive protein; Hb: Hemoglobin; ESR: Erythrocyte sedimentation rate; SES-CD: Simple Endoscopic Score for Crohn's Disease.