Development of a novel mouse constipation model

Figure 4 Measurement of carbon propulsion rate. A, B: All groups were used in the intestinal propulsion experiment and the distances by which black carbon was propelled, significantly decreased in state III mice compared to blank and saline control group at 15 d; C, D: measurement in all groups and the distance comparison at 20 d; E, F: In state III mice using domperidone suspensions for pretreatment, the carbon propulsion rates increased compared to those in state III mice at 15 d; G, H: measurement at 20 d (n = 4 for each group), ^aP < 0.05 vs blank control group; ^cP < 0.05 vs state III treated with domperidone.