Retrospective Study
Copyright ©The Author(s) 2016.
World J Gastroenterol. Mar 7, 2016; 22(9): 2828-2836
Published online Mar 7, 2016. doi: 10.3748/wjg.v22.i9.2828
Table 2 Characteristics and outcomes of patients with necrosectomy n (%)
CharacteristicsOutcomes
Demographics
Age (yr)46 (21-74)
Male sex220 (66)
BMI (kg/m2)28 (19-35)
Etiology
Biliary167 (50)
Alcoholic43 (13)
Others124 (37)
Onset of symptoms to first intervention
< 2 wk58 (17)
2-4 wk124 (37)
> 4 wk152 (46)
Severity of disease
APACHE-II score at admission8 (2-32)
Marshall score at admission2 (0-12)
Preoperative Marshall score2 (0-12)
SIRS at admission157 (47)
SIRS before operation177 (53)
Organ failure, n
Single organ failure at any time before surgery117 (35)
Single organ failure started at first week71/117
Persistent organ failure101/117
MOF at any time before surgery84 (25)
MOF started at first week46/84
Persistent MOF70/84
Laboratory parameters
CRP at admission (mg/L)200 (17-535)
CRP before surgery (mg/L)151 (8-478)
Preoperative acidosis pH < 7.267 (20)
Preoperative basic deficit > 5 mEq/L120 (36)
Preoperative hypocalcemia (calcium level < 1.87 mmol/L)148 (44)
Preoperative hypoproteinemia (albumin level < 30 g/L )171 (51)
Morphological criteria on CECT
Pancreatic necrosis285 (85)
Extrapancreatic necrosis only49 (15)
Percentage of necrosis, n
< 30%161/285
30%-50%75/285
> 50%49/285
CTSI before surgery8(4-10)
Gas bubble signs in the retroperitoneal space69 (21)
Microbiological data, n
Infected pancreatic necrosis214 (64)
Escherichia coli77/214
Enterococcus64/214
Klebsiella13/214
Baumanii19/214
Other bacillus15/214
Fungal infection15/214
Staphylococcus9/214
Pseudomonas aeruginosa2/214
Preoperative sepsis107 (32)
Operation data
Type of surgery
PCD102 (31)
Minimally invasive necrosectomy50 (16)
Open necrosectomy182 (53)
ASA classification
I88 (26)
II168 (50)
III78 (24)
Operation time, min138 (20-360)
Blood transfusion during operation91 (27)
Blood transfusion on the first day after surgery79 (23)
Postoperative data
Mortality53 (16)
Postoperative ICU stay (d)11 (0-170)
Whole hospital stay (d)53 (5-220)
Intra-abdominal hemorrhage50 (15)
Colonic fistula68 (20)
Progressive infection87 (26)