CD24 genetic variants contribute to overall survival in patients with gastric cancer

Table 3 Distributions of genotypes in three groups n (%)

	Controls	Cancer	P value	OR1 (95%CI)	Atrophy	P value	OR1 (95%CI)
P-534
C/C	271 (27.8)	181 (26.7)	-	Reference	29 (26.1)	-	Reference
C/A	488 (50.0)	358 (52.7)	0.099	1.1 (0.86-1.48)	62 (55.9)	0.204	1.2 (0.74-1.91)
A/A	217 (22.2)	140 (20.6)	0.145	0.9 (0.61-1.20)	20 (18.0)	0.328	0.8 (0.46-1.54)
C	1030 (52.8)	720 (53.0)	0.886	-	130 (54.1)	0.716	-
A	922 (47.2)	638 (47.0)		1.0 (0.86-1.14)	102 (45.9)		0.9 (0.72-1.25)
P170
C/C	419 (42.9)	295 (43.4)	-	Reference	60 (54.1)	-	Reference
C/T	439 (45.0)	308 (45.4)	0.277	1.1 (0.82-1.38)	37 (33.3)	0.082	0.6 (0.40-0.96)
T/T	118 (12.1)	76 (11.2)	0.369	0.9 (0.60-1.29)	14 (12.6)	0.724	0.9 (0.47-1.65)
C	1277 (65.4)	898 (66.1)	0.673	-	157 (70.7)	0.114	-
T	675 (34.6)	460 (33.9)		1.0 (0.83-1.12)	65 (29.3)		0.8 (0.58-1.06)
P1527
TG/TG	826 (84.6)	559 (82.3)	-	Reference	95 (85.6)	-	Reference
TG/del	142 (14.6)	117 (17.2)	0.069	1.3 (0.97-1.82)	15 (13.5)	0.940	0.9 (0.50-1.59)
del/del	8 (0.8)	3 (0.4)	0.162	0.4 (0.09-1.77)	1 (0.9)	0.935	0.9 (0.10-7.30)
TG	1794 (91.9)	1235 (90.9)	0.956	-	205 (92.3)	0.821	-
del	158 (8.1)	123 (9.1)		1.1 (0.88-1.45)	17 (7.7)		0.9 (0.56-1.58)
Haplotype2
ACTG	45.6	47.0	-	Reference	45.4	-	Reference
CTTG	33.6	33.7	0.946	1.0 (0.85-1.16)	28.7	0.407	0.9 (0.63-1.21)
CCTG	11.4	10.2	0.382	0.9 (0.71-1.14)	17.7	0.072	1.6 (0.99-2.37)
CCdel	8.0	9.1	0.370	1.1 (0.87-1.46)	7.7	0.919	1.0 (0.56-1.67)

Data are presented as frequency counts (percentage of total).

¹ORs of the genotypes were calculated adjusting for age, sex and H. pylori infection in logistic regression model;

²The haplotype was lined with P-534, P170 and P1527 and displayed as percentage.