Coagulopathy and transfusion therapy in pediatric liver transplantation

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Feb 14, 2016; 22(6): 2005-2023
Published online Feb 14, 2016. doi: 10.3748/wjg.v22.i6.2005

Table 6 Measures to reduce bleeding complications and transfusions during liver transplantation

Surgical phase	Procedure
Pre-operative	Erythropoietin
Pre-operative	Supplemental iron and folic acid
Intraoperative	Low CVP (fluid restriction, phlebotomy, vasopressors, Pringle maneuver)
	Acute intraoperative hemodilution
	Low transfusional trigger
	Drugs (rFVIIa, antifibrinolytics)
	Blood salvage
	Surgical technique
	TEG/ROTEM
Postoperative	Low transfusional trigger
	Minimize blood sampling
	Erythropoietin
	Supplemental iron and folic acid

CVP: Central venous pressure; rFVIIa: Activated recombinant factor VII; TEG: Thromboelastogram; ROTEM: Rotational thromboelastogram.

Citation: Nacoti M, Corbella D, Fazzi F, Rapido F, Bonanomi E. Coagulopathy and transfusion therapy in pediatric liver transplantation. World J Gastroenterol 2016; 22(6): 2005-2023
URL: https://www.wjgnet.com/1007-9327/full/v22/i6/2005.htm
DOI: https://dx.doi.org/10.3748/wjg.v22.i6.2005

Nacoti M, Corbella D, Fazzi F, Rapido F, Bonanomi E. Coagulopathy and transfusion therapy in pediatric liver transplantation. World J Gastroenterol 2016; 22(6): 2005-2023 [PMID: 26877606 DOI: 10.3748/wjg.v22.i6.2005]

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