Coagulopathy and transfusion therapy in pediatric liver transplantation

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Feb 14, 2016; 22(6): 2005-2023
Published online Feb 14, 2016. doi: 10.3748/wjg.v22.i6.2005

Table 2 Liver transplantation phases and coagulation status

Liver transplantation phases	Coagulation status
Pre-existing coagulation disorders	Developmental hemostasis
	Rebalanced hemostasis in chronic disease
	Unpredictable effect in acute liver failure
Liver transplantation surgery	Coagulopathy of surgical trauma
Pre-anhepatic phase	Surgical challenge
Anhepatic phase	Hyperfibrinolysis (lack tPa clearance)
Reperfusion phase	Hyperfibrinolysis (lack tPa clearance)
	Ischemic-reperfusion syndrome
	Heparin-like effect
	tPa release
After liver transplantation surgery	Tendency to thrombotic state (days 1-14 after liver transplantation)
After liver transplantation surgery	Recovery of coagulation activity in 1 mo

Citation: Nacoti M, Corbella D, Fazzi F, Rapido F, Bonanomi E. Coagulopathy and transfusion therapy in pediatric liver transplantation. World J Gastroenterol 2016; 22(6): 2005-2023
URL: https://www.wjgnet.com/1007-9327/full/v22/i6/2005.htm
DOI: https://dx.doi.org/10.3748/wjg.v22.i6.2005

Nacoti M, Corbella D, Fazzi F, Rapido F, Bonanomi E. Coagulopathy and transfusion therapy in pediatric liver transplantation. World J Gastroenterol 2016; 22(6): 2005-2023 [PMID: 26877606 DOI: 10.3748/wjg.v22.i6.2005]

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