Variable outcome in infantile-onset inflammatory bowel disease in an Asian cohort

Table 2 Comparison of disease characteristics, management and final outcome of infantile-onset inflammatory bowel disease and children with onset of disease after 12 mo of age

	Onset before 1 year, n (%)	Onset after 1 year, n (%)	P value
n	6	41
Median age at diagnosis (yr)	0.44	8.34
Duration of follow-up (yr), median (range)	6.1 (1.4-19.6)	8.3 (1.0-16.6)
Male	4	22
Female	2	19
Crohn’s disease	3	22
Ulcerative colitis	2	19
IBD-unclassified	1	0
Initial presentation, n (%)
Bloody diarrhea	6 (100)	23 (55)	0.039
Perianal disease	3 (50)	8 (19)	0.11
Extraintestinal involvement
Autoimmune liver disease	0 (0)	8 (19)	0.31
Therapy
Biologics-infliximab	3 (50)	15 (36)	0.40
Surgery	3 (50)	12 (29)	0.27
Disease status at final review
Inactive disease or in clinical remission	3 (50)	27 (66)	0.40
Discontinuation of immunosuppression
Yes	3 (50)	5 (12)	0.053
No	3 (50)	36 (88)

IBD: Inflammatory bowel disease.