Hepatoprotective and antioxidant effects of lycopene on non-alcoholic fatty liver disease in rat

doi:10.3748/wjg.v22.i46.10180

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Dec 14, 2016; 22(46): 10180-10188
Published online Dec 14, 2016. doi: 10.3748/wjg.v22.i46.10180

Table 2 Effect of lycopene on liver antioxidant enzyme-specific activities, antioxidant and lipid peroxidation levels

Group	SOD (U/mgprot)	GSH (mg/gprot)	MDA (nmol/mgprot)
Control	131.42 ± 16.24	6.76 ± 1.54	3.46 ± 1.11
Model	77.70 ± 7.63^b	2.55 ± 0.78^b	7.58 ± 3.10^b
Ly 5 mg/kg	90.95 ± 9.56^c	2.68 ± 1.26	5.24 ± 1.46^d
Ly 10 mg/kg	109.52 ± 11.34^d	3.76 ± 0.91^c	4.13 ± 1.13^d
Ly 20 mg/kg	121.25 ± 10.68^d	4.79 ± 1.51^d	3.45 ± 1.39^d

Data are expressed as mean ± SD (n = 12) for each group.

^bP < 0.01 vs control group;

^cP < 0.05,

^dP < 0.01 vs model group. Ly: Lycopene; SOD: Superoxide dismutase; GSH: Glutathione; MDA: Malondialdehyde.

Citation: Jiang W, Guo MH, Hai X. Hepatoprotective and antioxidant effects of lycopene on non-alcoholic fatty liver disease in rat. World J Gastroenterol 2016; 22(46): 10180-10188
URL: https://www.wjgnet.com/1007-9327/full/v22/i46/10180.htm
DOI: https://dx.doi.org/10.3748/wjg.v22.i46.10180