Collision tumor of hepatocellular carcinoma and neuroendocrine carcinoma involving the liver: Case report and review of the literature

Table 1 Summary of previously reported cases of hepatocellular carcinoma plus neuroendocrine carcinoma involving the liver

Ref.	Age/sex	Clinical manifestations	Underlying liver disease	Tumor size	Type	Treatment	Survival
Barsky/1984[4]	43/M	RUQ swelling	Hepatitis B	Huge1	Combined	Chemotherapy	26 mo
Artopoulos/1994[5]	69/M	RUQ pain	Hepatitis B	10 cm	Combined	Operation	NM
Vora/1999[6]	63/M	Abdominal pain and jaundice	Liver cirrhosis	10 cm	Combined	Operation	Died during admission
Ishida/2003[3]	72/M	No symptom	Hepatitis C	3 cm, 1.5 cm	Collision	Operation	NM
Yamaguchi/2004[7]	71/M	No symptom	Hepatitis C	4.1 cm2, 4.5 cm3	Combined	Operation	NM
Garcia/2006[2]	50/M	No symptom	Hepatitis C	5 cm	Collision	Operation and chemotherapy	NM
Yang/2009[8]	65/M	Epigastric pain	Hepatitis B	7.5 cm	Combined	Operation	Died after 1 yr
Aboelenen/2014[9]	51/M	Abdominal pain	Hepatitis C	7.5 cm	Combined	Operation	No recurrence up to 6 mo

¹Large mass involving the right lobe;

²Combined tumor of hepatocellular carcinoma (HCC) and neuroendocrine carcinoma;

³Pure HCC. RUQ: Right upper quadrant; NM: Not mentioned.