Hepatitis C in non-hepatic solid organ transplant candidates and recipients: A new horizon

Table 3 Drug interactions with immunosuppressants and other common post-transplant medications

	SOF	SMV	LDV	PTV/r + OMB + DSV	DCV
Cyclosporine	*	***	**	**	*
Tacrolimus	*	**	**	**	*
Sirolimus	*	**	**	**	*
MMF	*	*	*	**	*
Azathioprine	*	*	*	*	*
Prednisone	*	**	*	**	*
Fluconazole	*	***	*	*	*
Voriconazole	*	***	*	***	**
Posaconazole	*	***	*	***	**
PPI	*	*	**	**	*

SOF: Sofosbuvir; SMV: Simeprevir; LDV: Ledipasvir; PTV: Paritaprevir; r: Ritonavir; OMB: Ombitasvir; DSV: Dasabuvir; DCV: Daclatasvir; PPI: Proton pump inhibitor. ***Contraindicated, do not co-administer; **Potential for interaction, use with caution; may require altered dosing; *No clinically significant interaction.