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Copyright ©The Author(s) 2016.
World J Gastroenterol. Jan 28, 2016; 22(4): 1477-1486
Published online Jan 28, 2016. doi: 10.3748/wjg.v22.i4.1477
Table 1 Summary of host restriction factors for hepatitis C virus
Host restriction factorHCV life cycle stepIFN induceble or notRef.
IFITM1EntryY[19]
IFITM1ReplicationY[38]
Ficolin-2EntryN[20]
EMREntryN[21]
MoesinReplicationN[21]
TRIM14ReplicationY[16]
NOS2ReplicationY[16]
IFITM3ReplicationY[16]
ISG56ReplicationY[38]
ViperinReplicationY[17,58,59]
CIDEBReplicationN[33,63]
Xrn1ReplicationN[66-70]
Xrn2ReplicationN[67,68]
APOBEC3GReplicationN[76,77]
Sac1ReplicationN[83,84]
ACBD3ReplicationN[91]
SOCS3ReplicationN[97]
MSR1ReplicationN[103]
BST-2Particle production and releaseY[125-127]
PKDSecretion and releaseN[132]
YB-1Particle productionN[137,138]