Observational Study
Copyright ©The Author(s) 2016.
World J Gastroenterol. Oct 7, 2016; 22(37): 8406-8413
Published online Oct 7, 2016. doi: 10.3748/wjg.v22.i37.8406
Table 3 Predictive factors for sustained virological response, univariate analysis n (%)
VariableSVR n = 42No SVR n = 66P value
Age (yr), median48.1 (22.1-68.3)54.7 (22.1-67.3)< 0.001
Female gender22 (52.4)42 (63.6)0.246
Urban residence (%)37 (88.1)41 (62.1)0.004
Baseline ALT (mg/dL), median79 (16-890)75 (17-231)0.688
Baseline HCV-RNA, median6.2 (4.15-7.3)6.2 (4.8; 7.3)0.167
Mild/moderate fibrosis18 (75.0)20 (48.8)0.107
IL28B type CC (%)17 (40.5)2 (3.0)< 0.001
Absence of core mutations - DW10 (23.8)3 (4.5)0.005
Presence of any core mutation, (%)32 (76.2)63 (95.5)0.005
Viral mutation in core 91 only (%)15 (60.0)25 (84.3)0.024
Viral mutation in core 70 only (%)2 (16.7)6 (66.7)0.032
RVR (%)13 (31.0)1 (1.5)< 0.001
EVR (%)37 (88.1)6 (9.1)< 0.001