Carbonic anhydrase enzymes II, VII, IX and XII in colorectal carcinomas

doi:10.3748/wjg.v22.i36.8168

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 28, 2016; 22(36): 8168-8177
Published online Sep 28, 2016. doi: 10.3748/wjg.v22.i36.8168

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Figure 2 Effect of CA II, CA VII, CA IX and CA XII expression on survival of colorectal patients. Survival of 539 colorectal cancer patients operated between 1983-2001 in Helsinki University Hospital was recorded and the expression of carbonic anhydrases (CA II, CA VII, CA IX and CA XII) was evaluated from immunohistochemical stainings of tumor specimens. The effects of CA expressions on survival were analyzed by Kaplan-Meier analyses. Both CA II staining intensity (P = 0.004) and extent (P = 0.022) correlated with the patient survival. A weak correlation was also found between the CA XII staining intensity and survival (P = 0.020).

Citation: Viikilä P, Kivelä AJ, Mustonen H, Koskensalo S, Waheed A, Sly WS, Pastorek J, Pastorekova S, Parkkila S, Haglund C. Carbonic anhydrase enzymes II, VII, IX and XII in colorectal carcinomas. World J Gastroenterol 2016; 22(36): 8168-8177
URL: https://www.wjgnet.com/1007-9327/full/v22/i36/8168.htm
DOI: https://dx.doi.org/10.3748/wjg.v22.i36.8168