Roles of hepatocyte nuclear factors in hepatitis B virus infection

Figure 2 Schematic representation of transcription factor-binding regions in HBV enhancers and promoters. The inner circle represents the 3.2-kb hepatitis B virus (HBV) genome (partially double-stranded circular DNA). The outer lines indicate the four open reading frames (ORFs). There are four viral promoters located just before the ORFs and two enhancers (Enh I and Enh II). Various transcription factors can bind to the enhancers and promoters as indicated. The boxes represent competing binding regions.