Smaller tumor size is associated with poor survival in T4b colon cancer

Table 5 Demographics of patients from the Fudan University Shanghai Cancer Center database with T4bN0-2M0 colon cancer, according to tumor size n (%)

Characteristic	Tumor size (cm)				P value
	Total (n = 101)	≤4.0 (n = 18)	4.0-7.0 (n = 39)	≥7.0 (n = 44)
Median follow-up (mo)	49	46	51	44
IQR	33-62	27-72	31-61	33-62
Sex					0.582
Male	59 (58.4)	9 (50.0)	22 (56.4)	28 (63.6)
Female	42 (41.6)	9 (50.0)	17 (43.6)	16 (36.4)
Age at diagnosis (yr)					0.245
≤ 60	33 (32.7)	3 (16.7)	13 (33.3)	17 (38.6)
> 60	68 (67.3)	15 (83.3)	26 (66.7)	27 (61.4)
Primary site					0.668
Right colon	50 (49.5)	8 (44.4)	18 (46.2)	24 (54.5)
Left colon	51 (50.5)	10 (55.6)	21 (53.8)	20 (45.5)
Histology type					0.262
Adenocarcinoma	88 (87.1)	16 (88.9)	35 (89.7)	37 (84.1)
Mucinous adenocarcinoma	10 (9.9)	1 (5.6)	2 (5.1)	7 (15.9)
Signet-ring cell carcinoma	3 (3.0)	1 (5.6)	2 (5.1)	0 (0.0)
Pathology grade					0.567
High/Moderate	72 (71.3)	11 (61.1)	29 (74.4)	32 (72.7)
Poor/Undifferentiated	29 (28.7)	7 (38.9)	10 (25.6)	12 (27.3)
N stage					0.210
N0	43 (42.6)	4 (22.2)	20 (51.3)	19 (43.2)
N1	34 (33.7)	10 (55.6)	10 (25.6)	14 (31.8)
N2	24 (23.8)	4 (22.2)	9 (23.1)	11 (25.0)
LNH					0.109
≤ 18	56 (55.4)	14 (77.8)	20 (51.3)	22 (50.0)
> 18	45 (44.6)	4 (22.2)	19 (48.7)	22 (50.0)
Lymphovascular invasion					0.176
Positive	37 (36.6)	10 (55.6)	12 (30.8)	15 (34.1)
Negative	64 (63.4)	8 (44.4)	27 (69.2)	29 (65.9)
Perineural invasion					0.906
Positive	24 (23.8)	5 (27.8)	9 (23.1)	10 (22.7)
Negative	77 (76.2)	13 (72.2)	30 (76.9)	34 (77.3)

IQR: Interquartile range; LNH: Number of lymph nodes harvested; FUSCC: Fudan University Shanghai Cancer Centre.