Smaller tumor size is associated with poor survival in T4b colon cancer

Table 4 Univariate and multivariate survival analyses of patients in the Surveillance, Epidemiology and End Results database with T4bN0M0 colon cancer

Variable	Univariateanalysis		Multivariateanalysis
	5-yr CSS	P value	HR	95%CI	P value
Sex		0.443			NI
Male	67.7%
Female	71.2%
Year of diagnosis		0.473			NI
1988-1999	71.9%
2000-2003	66.7%
Race		0.388			NI
White	70.0%
Black	62.2%
Other1	73.0%
Primary site		0.819			NI
Right colon	70.1%
Left colon	68.6%
Histological type		0.401			NI
Adenocarcinoma	69.0%
Mucinous adenocarcinoma	72.1%
Signet-ring cell carcinoma	40.0%
Pathology grade		0.552			NI
High	80.6%
Moderate	68.5%
Poor	66.0%
Undifferentiated	66.7%
Age at diagnosis (yr)		0.002			0.004
≤ 60	74.1%		1.000	reference
> 60	65.5%		1.441	1.127-1.841
LNH		0.029			0.063
≤ 18	64.3%		1.000	reference
> 18	75.1%		0.795	0.624-1.013
Tumor size, cm		0.024			0.048
≤ 4.0	58.4%		1.000	reference
4.0-7.0	69.3%		0.790	0.554-1.127	0.194
≥ 7.0	72.4%		0.656	0.464-0.926	0.017

¹Includes Native American, Asian, Pacific Islander and Unknown. CSS: CANCER-specific survival; LNH: NUMBER of lymph nodes harvested; NI: NOT included in the multivariate survival analysis.