Management of a large mucosal defect after duodenal endoscopic resection

Table 2 Outcomes of duodenal endoscopic submucosal dissection for nonampullary duodenal neoplasm in the literature n (%)

Ref.	Year	No. lesions	Mean tumor size (mm)	R0 resection rate	Operation time (min)	Perforation		Delayed bleeding	Surgical conversion	Prophylactic closure
Honda et al[23]	2009	9	23.7	9 (100)	80.0	2 (22.2)	Immediate (1), delayed (1)	2 (22)	1 (11)	-
Takahashi et al[43]	2009	4	20.5	4 (100)	-	2 (50)	Immediate (2)	0 (0)	0 (0)	-
Endo et al[44]	2010	5	10.0	5 (100)	-	1 (20)	Immediate (1)	0 (0)	0 (0)	-
Jung et al[42]	2013	14	17.1	12 (85.7)	32.0	5 (35.7)	Immediate (3), delayed (2)	1 (7.1)	2 (14.3)	-
Matsumoto et al[5]	2014	15	12.9	13 (86.7)	86.5	3 (20)	Immediate (3)	3 (20)	2 (13.3)	4 of the 5 cases of lesion [4 (26.7)] located in descending part of the duodenum with hemoclip
Yamamoto et al[4]	2014	30	13.7	27 (90.0)	79.5	3 (10)	Immediate (2), delayed (1)	0 (0)	1 (3)	Limited cases of lesions located in the distal of duodenum with hemoclip
Seo et al[41]	2014	7	-	-	-	3 (75)	Immediate (3)	0 (0)	0 (0)	-
Kakushima et al[54]	2014	13	Median 13.5	13 (100)	-	4 (40)	Immediate (3), delayed (1)	0 (0)	1 (7.7)	-
Park et al[93]	2015	6	-	5 (83.3)	Median 41.5	2 (33.3)	-	0 (0)	-	-
Hoteya et al[15]	2015	63	24.6	55 (87.3)	116.4	21 (31.3)	-	11 (17.5)	4 (6.2)	23 patients [23 (36.5)] with hemoclip
Ishii et al[45]	2015	16	Median 13	13 (81.3)	Median 66	1 (6.3)	Immediate (1)	0 (0)	1 (6.3)	10 patients [10 (93)] with hemoclip (8 patients) and PGA sheets (2 patients)
Nonaka et al[29]	2015	8	Median 18	-	-	2 (25.0)	Delayed (1)	0 (0)	1 (12.5)	Immediate closure was performed in 99 lesions (99/121) including 113 EMR cases with hemoclip

PGA: Polyglycolic acid; EMR: Endoscopic mucosal resection.