Long-term outcomes and prognostic factors of patients with obstructive colorectal cancer: A multicenter retrospective cohort study

Table 4 Result of the univariate and multivariate analysis of prognostic factors for cancer-specific survival

Factor		n	Univariate analysis			Multivariate analysis
			3-yr CSS	5-yr CSS	P value	HR(95%CI)	P value
Gender	M	141	88.3%	80.8%	0.924
	F	93	87.8%	79.7%
Age (yr)	≥ 75	96	82.2%	71.6%	0.027	1.464 (0.647-3.310)	0.360
	< 75	138	91.9%	85.4%
ASA-PS	1	71	86.0%	83.5%	0.710
	2-3	163	89.0%	78.7%
BMI (kg/m2)	≥ 25	28	92.0%	85.8%	0.389
	< 25	193	87.3%	80.0%
Serum albumin (g/dL)	≤ 4.0	172	85.6%	82.6%	0.536
	> 4.0	48	87.7%	76.2%
CEA (mg/dL)	≥ 5.0	102	86.7%	80.0%	0.715
	< 5.0	113	90.5%	82.0%
Decompression	+	183	88.4%	81.7%	0.514
	-	51	87.1%	74.8%
Location of tumor	Right side	69	82.6%	70.5%	0.103
	Left side	165	90.4%	84.3%
Tumor size (mm)	≥ 50	99	84.1%	76.9%	0.291
	< 50	121	90.4%	85%
Differentiation of tumor	tub1, tub2	222	89.9%	82.5%	0.001	6.282 (1.584-24.909)	0.009
	por, muc	12	50.0%	50.0%
Depth of tumor	T3	108	95.7%	92.3%	0.001	3.458 (1.324-9.031)	0.011
	T4	126	81.1%	69.2%
Intramural lymphatic invasion	+	157	90.8%	82.7%	0.449
	-	73	86.9%	79.4%
Intramural vascular invasion	+	164	94.2%	90.1%	0.152
	-	70	85.9%	76.7%
Lymph node involvement	+	120	92.5%	82.9%	0.332
	-	114	84.0%	77.7%
Lymph node dissection	D0, D1	31	60.7%	60.7%	0.014	0.958 (0.300-3.056)	0.942
	D2, D3	199	90.4%	83.0%
No. of lymph nodes harvested	< 12	73	83.3%	78.3%	0.314
	≥ 12	151	91.1%	81.0%
Postoperative complication	+	78	85.9%	75.6%	0.644
(≥ Grade 2)	-	156	89%	82.5%
Anastomotic leakage	+	18	100%	100%	0.069
	-	191	87.1%	78.7%
Curability	R0	219	91.3%	84.7%	< 0.001	6.162 (1.692-22.445)	0.006
	R1	15	39.7%	19.9%
Adjuvant chemotherapy	+	91	87.7%	81.8%	0.800
	-	143	88.8%	79.4%