Long-term outcomes and prognostic factors of patients with obstructive colorectal cancer: A multicenter retrospective cohort study

Table 3 Result of the univariate and multivariate analysis of risk factors for recurrence

Factor		n	Univariate analysis			Multivariate analysis
			3-yr RFS	5-yr RFS	P value	HR (95%CI)	P value
Gender	M	141	59.2%	47.6%	0.409
	F	93	66.8%	54.7%
Age (yr)	≥ 75	96	55.0%	42.4%	0.011	1.228 (0.659-2.290)	0.518
	< 75	138	67.3%	55.9%
ASA-PS	1	71	75.7%	64.8%	0.017	2.234 (1.101-4.535)	0.026
	2-3	163	56.6%	44.6%
BMI (kg/m2)	≥ 25	28	66.0%	49.7%	0.951
	< 25	193	62.7%	52.7%
Serum albumin (g/dL)	≤ 4.0	172	54.9%	41.3%	0.001	2.967 (1.342-6.560)	0.007
	> 4.0	48	79.7%	73.1%
CEA (mg/dL)	≥ 5.0	102	52.4%	44.8%	0.052
	< 5.0	113	74.1%	54.2%
Decompression	+	183	62.9%	50.7%	0.572
	-	51	60.5%	50.4%
Location of tumor	Right side	69	62.5%	55.5%	0.738
	Left side	165	62.1%	48.7%
Tumor size (mm)	≥ 50	99	61.0%	48.8%	0.384
	< 50	121	63.9%	54.1%
Differentiation of tumor	tub1,tub2	222	63.7%	51.2%	0.080
	por, muc	12	36.7%	36.7%
Depth of tumor	T3	108	73.5%	64.7%	0.001	2.728 (1.467-5.072)	0.002
	T4	126	53.0%	38.7%
Intramural lymphatic invasion	+	157	61.4%	53.2%	0.600
	-	73	64.4%	45.2%
Intramural vascular invasion	+	164	60.3%	49.3%	0.683
	-	70	68.1%	57.4%
Lymph node involvement	+	120	65.7%	47.4%	0.856
	-	114	59.1%	53.2%
Lymph node dissection	D0,D1	31	44.3%	44.3%	0.067
	D2,D3	199	64.7%	50.8%
No. of lymph nodes harvested	< 12	73	54.8%	44.5%	0.085
	≥ 12	151	66.4%	52.5%
Postoperative complication	+	78	57.3%	44.7%	0.071
(≥ Grade 2)	-	156	64.7%	53.5%
Anastomotic leakage	+	18	71.1%	56.9%	0.562
	-	191	61.7%	50.0%
Curability	R0	219	66.4%	54.8%	< 0.001	6.555 (1.344-31.970)	0.020
	R1	15	7.6%	0.0%
Adjuvant chemotherapy	+	91	66.2%	55.6%	0.069
	-	143	59.8%	47.2%