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©The Author(s) 2016.
World J Gastroenterol. May 28, 2016; 22(20): 4936-4945
Published online May 28, 2016. doi: 10.3748/wjg.v22.i20.4936
Published online May 28, 2016. doi: 10.3748/wjg.v22.i20.4936
Table 2 Overview of the molecular testing results n (%)
| Marker | Localization | Advanced adenoma1 | Early carcinoma2 | Late carcinoma3 |
| MSI | Proximal | 0 (0) | 5 (20) | 7 (24.14) |
| Distal | 0 (0) | 0 (0) | 0 (0) | |
| Rectum | 0 (0) | 0 (0) | 0 (0) | |
| CIMP | Proximal | 13 (30.95) | 15 (65.22) | 16 (59.25) |
| Distal | 7 (16.28) | 10 (45.45) | 6 (35.29) | |
| Rectum | 2 (13.33) | 11 (50.22) | 8 (47.06) | |
| BRAF | Proximal | 7 (10.94) | 4 (17.39) | 7 (24.14) |
| Distal | 1 (1.49) | 0 (0.00) | 0 (0.00) | |
| Rectum | 4 (17.39) | 1 (4.20) | 2 (11.11) | |
| KRAS | Proximal | 25 (35.71) | 11 (44.00) | 15 (51.72) |
| Distal | 28 (43.08) | 11 (44.00) | 4 (23.53) | |
| Rectum | 12 (50.00) | 10 (41.67) | 7 (38.88) | |
| APC | Proximal | 24 (35.82) | 5 (20.83) | 5 (17.24) |
| Distal | 22 (34.38) | 8 (34.78) | 6 (37.5) | |
| Rectum | 9 (37.50) | 7 (29.17) | 8 (44.44) | |
| TP53 | Proximal | 5 (7.46) | 8 (33.33) | 8 (27.59) |
| Distal | 2 (3.13) | 8 (34.78) | 8 (50.00) | |
| Rectum | 1 (4.17) | 11 (45.83) | 10 (55.55) |
- Citation: Minarikova P, Benesova L, Halkova T, Belsanova B, Suchanek S, Cyrany J, Tuckova I, Bures J, Zavoral M, Minarik M. Longitudinal molecular characterization of endoscopic specimens from colorectal lesions. World J Gastroenterol 2016; 22(20): 4936-4945
- URL: https://www.wjgnet.com/1007-9327/full/v22/i20/4936.htm
- DOI: https://dx.doi.org/10.3748/wjg.v22.i20.4936