©The Author(s) 2016.
World J Gastroenterol. Jan 14, 2016; 22(2): 833-841
Published online Jan 14, 2016. doi: 10.3748/wjg.v22.i2.833
Published online Jan 14, 2016. doi: 10.3748/wjg.v22.i2.833
Table 1 Nomenclature of selected chemokines, coding chromosomal location, major function and interacting receptor
| Synonymes | Location | Major function | Receptor | |
| CC Chemokine | ||||
| CCL3 | MIP-1α/LD78α | 17q11.2 | Inflammation | CCR1 |
| CCL4 | MIP-1β | 17q12 | Inflammation | CCR1 |
| CCR5 | ||||
| CCL5 | RANTES | 17q12 | Inflammation | CCR5 |
| CCL19 | MIP-3β/ELC/Exodus-3 | 9p13.3 | Homing | CCR7 |
| CCL20 | MIP-3α/LARC/Exodus-1 | 2q36.3 | Homing, Inflammation | CCR6 |
| CCL21 | 6Ckine/SLC/Exodus-2 | 9p13.3 | Homing | CCR7 |
| CCL25 | TECK/Ckβ15 | 19p13.2 | Homing | CCR9 |
| CXC Chemokine | ||||
| CXCL8 | IL-8 | 4q13.3 | Inflammation, Angiogenesis1 | CXCR1 |
| CXCR2 | ||||
| CXCL9 | MIG | 4q21.1 | Inflammation, | CXCR3 |
| Angiogenesis2 | ||||
| CXCL10 | IP-10 | 4q21.1 | Inflammation, | CXCR3 |
| Angiogenesis2 | ||||
| CXCL11 | I-TAC | 4q21.1 | Inflammation, | CXCR3 |
| Angiogenesis2 | CXCR7 | |||
| CXCL12 | SDF-1α/β | 10q11.21 | Homing | CXCR4 |
| CXCR7 | ||||
| CXCL13 | BLC/BCA-1 | 4q21.1 | Homing | CXCR5 |
| CX3C Chemokine | ||||
| CX3CL1 | Fractalkine | 16q13 | Inflammation | CX3CR1 |
| C-Chemokine | ||||
| XCL1 | Lymphotactin/SCM-1α | 1q24.2 | Homing | XCR1 |
| XCL2 | SCM-1β | 1q24.2 | Homing | XCR1 |
- Citation: Frick VO, Rubie C, Keilholz U, Ghadjar P. Chemokine/chemokine receptor pair CCL20/CCR6 in human colorectal malignancy: An overview. World J Gastroenterol 2016; 22(2): 833-841
- URL: https://www.wjgnet.com/1007-9327/full/v22/i2/833.htm
- DOI: https://dx.doi.org/10.3748/wjg.v22.i2.833