Role of estrogen receptor β selective agonist in ameliorating portal hypertension in rats with CCl4-induced liver cirrhosis

Table 1 Biochemical parameters of the different treatment groups

Group	ALT (U/L)	AST (U/L)	Bilirubin (mg/dL)	Albumin (g/L)	BUN (mmol/L)	Scr (μmol/L)
Control (n = 8)	43.3 ± 7.7	124 ± 14	0.3 ± 0.1	34.1 ± 3.4	8.7 ± 1.2	22.4 ± 4.0
OVX + CCl4 (n = 6)	166 ± 10.1ab	439 ± 19ab	3.4 ± 0.3ab	21.5 ± 2.8ab	16.7 ± 1.8ab	35.0 ± 4.7ab
OVX + CCl4 + DPN (n = 7)	86.1 ± 8.7a	211 ± 15a	1.7 ± 0.2a	31.0 ± 3.3	9.6 ± 1.5	24.9 ± 4.5
OVX + CCl4 + DPN + PHTPP (n = 6)	168 ± 10.2ab	436 ± 23ab	3.3 ± 0.4ab	20.8 ± 2.0ab	16.5 ± 2.1ab	37.5 ± 4.6ab

^aP < 0.05 vs control group;

^bP < 0.05 vs DPN group. OVX: Ovariectomized; SVR: Systemic vascular resistance; DPN: Diarylpropionitrile.