Growth hormone abolishes the negative effects of everolimus on intestinal wound healing

Figure 5 Zymographic activities of the pro-inflammatory matrix-metalloproteinases MMP2 and MMP9. Zymography gel showing increased proteolytic activity under treatment with everolimus which is reduced by simultaneous treatment with human growth hormone (hGH) (A). Numeric calculation of the proteolytic activity of MMP2 (B) and MMP9 (C). V: vehicle, E: everolimus 3.0 mg/kg, E+GH: everolimus 3.0 mg/kg + hGH 2.5 mg/kg; V vs E, E + GH vs E, ^aP < 0.05.