Early detection of hepatocellular carcinoma co-occurring with hepatitis C virus infection: A mathematical model

doi:10.3748/wjg.v22.i16.4168

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 22, Issue 16

This Article

Academic Content and Language Evaluation of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Supplementary Materials of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (7162)

All Articles published online

The chart showing PDF series, WORD series, HTML series, Figures (1-5) series, Tables (1-7) series.

Item

Count

PDF

593

WORD

271

HTML

3429

Figures (1-5)

167

Tables (1-7)

167

Sum=4627

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

1014

Download

1521

Sum=2535

Apr 28, 2016 (publication date) through Apr 25, 2024

Times Cited of This Article

Times Cited (2)

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Case Control Study

World J Gastroenterol. Apr 28, 2016; 22(16): 4168-4182
Published online Apr 28, 2016. doi: 10.3748/wjg.v22.i16.4168

Table 7 Final reduced disease logistic predictive models based on binary classifier with the most significant markers (achieved regression P < 0.05)

	Final reduced model (with relevant terms)	Best threshold
Disease vs Control	(-11 + 6.83 × Prot + 0.00129 × sTNF + 0.283 × AFP)	0.764
HCC vs LC	(-11.3 + 7.38 × Prot + 0.00108 × sICAM + 0.2574 ×β-catenin + 0.01597 × AFP)	0.655
HCC vs HCV	[-11.91 + 3.222 × Prot + 0.001518 × sICAM + (6.481 × 10^-4) × sTNF + 0.291 ×β-catenin + 0.0193 × AFP]	0.712
HCC vs Non-HCC	[-12.27 + 3.299 × Prot + 0.001548 × sICAM + (6.803 × 10^-4) × sTNF + 0.2936 ×β-catenin + 0.0198 × AFP]	0.378
HCV vs Control	(-10.84 + 6.803 × Prot + 0.00126 × sTNF + 0.2783 × AFP)	0.764
LC vs CHC	[-10.16 + (-4.487) × Prot + 0.002086 × sICAM + 0.001858 × sTNF + (-0.2984) ×β-catenin + 0.02169 × AFP]	0.582
CHC vs Control	(-9.353476 + 6.63414 × Prot + 0.001111 × sTNF + 0.24604 × AFP)	0.341
HCC vs CHC	[-10.40 + 1.416 × Prot + 0.002024 × IL-8 + 0.004096 × sICAM + (4.251 × 10^-4) × sTNF + 0.2567 ×β-catenin + 0.02442 × AFP]	0.745

CHC: Chronic hepatitis C; LC: Liver cirrhosis; AFP: α-fetoprotein; HCC: Hepatocellular carcinoma; HCV: Hepatitis C virus.; sICAM-1: Soluble intercellular adhesion molecule; sTNF: Soluble tumor necrosis factor.

Citation: Zekri ARN, Youssef ASED, Bakr YM, Gabr RM, Ahmed OS, Elberry MH, Mayla AM, Abouelhoda M, Bahnassy AA. Early detection of hepatocellular carcinoma co-occurring with hepatitis C virus infection: A mathematical model. World J Gastroenterol 2016; 22(16): 4168-4182
URL: https://www.wjgnet.com/1007-9327/full/v22/i16/4168.htm
DOI: https://dx.doi.org/10.3748/wjg.v22.i16.4168