Intestinal histoplasmosis in immunocompetent adults

Table 2 Symptoms, signs and sites of involvement

	Case A	Case B	Case C	Case D
Symptoms
Fever	No	Yes	Yes	Yes
Temperature (°C)		35.3-40.3	35.8-38.7	35-40.3
Night sweat	No	Yes	Yes	Not reported
Chills	No	No	No	Yes
Antibiotic1	Moxifloxacin2	Levofloxacin3	Anqi4	Penicillin5, Amikacin5
	Metronidazole2			Azithromycin5
				Levofloxacin6
				Ceftriaxone5, Xianshu7
Abdominal pain	Right abdomen	No	Yes	Whole abdomen
Abdominal distention	Yes	No	Yes	Upper abdomen
Diarrhea	No	No	No	Yes8
Anorexia	Yes	Yes	Yes	Not reported
Pharyngalgia	No	Yes	No	Not reported
Cough	No	Yes	No	No
Expectoration	No	Yes	No	No
Weight loss	Not apparent	15 kg	4 kg	10 kg
Signs
Lymphadenectasis	No	Yes9	No	Yes
Abdominal tension	No	No	No	Yes
Hepatomegaly	No	Not palpable	Yes10	Yes
Splenomegaly	No	Yes11	Yes12	Yes
(Rebound) tenderness	No	No	No	Yes
Shifting dullness	Negative	Negative	Negative	Positive
Involvement
Bone marrow		√	√	√
Pulmonary
Colon	√	√	√	√
Terminal ileum		√	√	√

¹Empirically used, but invalid;

²For 5 d, dosage unknown;

³0.4 g iv daily for 26 d;

⁴Amoxicillin and potassium clavulanate tablets 0.3125 g tid po for 1 wk;

⁵Dosage unknown;

⁶0.4 g iv daily for 28 d in our hospital; dosage unknown in other hospital;

⁷Cefoperazone sulbactam sodium 2.0 g iv bid for 8 d then 2.0 g iv tid for 7 d;

⁸Black watery stool with amount unknown, 7-10 times per day;

⁹1 × 1 cm soft lymphatic node without adhesion in the left armpit;

¹⁰3 cm below the right rib border and 5 cm below the xiphoid;

¹¹5 cm below the left rib border;

¹²3 cm below the left rib border.