Oncogenic Wnt3a expression as an estimable prognostic marker for hepatocellular carcinoma

Table 4 Univariate and multivariable analysis of prognostic factors in hepatocellular carcinoma for 5-year survival

Variable	Univariate analysis			Multivariable analysis
	HR	P >|z|	95%CI	HR	P > |z|	95%CI
Age (yr)
≤ 60 vs > 60	0.828	0.662	0.355-1.930
Gender
Male vs female	1.005	0.990	0.440-2.296
Differentiation
Low vs high	1.037	0.914	0.539-1.993
Tumor number
Single vs multiple	0.867	0.720	0.397-1.893
Liver cirrhosis
Absent vs present	2.101	0.035	1.053-4.195	2.021	0.033	1.057-3.864
HBV infection
Absent vs present	0.327	0.029	0.120-0.892	0.325	0.010	0.138-0.765
Periportal embolus
Absent vs present	0.499	0.360	0.113-2.210
AFP (ng/mL)
< 400 vs≥ 400	0.938	0.725	0.655-1.342
TNM staging
I-II vs III-IV	0.686	0.318	0.328-1.436
Wnt3a expression
Low vs high	5.656	< 0.001	2.682-11.926	3.651	< 0.001	1.973-6.757

HBV: Hepatitis B virus; AFP: α-fetoprotein; TNM: Tumor-node-metastasis.