Resveratrol and fenofibrate ameliorate fructose-induced nonalcoholic steatohepatitis by modulation of genes expression

Figure 4 Effect of fenofibrate (100 mg/kg) and resveratrol (70 mg/kg) alone and in combination (half doses) on liver MDA (A), GSH (B) and SOD (C) in fructose-induced NASH in rats. Values are mean ± SE, n = 8-12 rats. The significance of the difference between means was tested by ANOVA followed by Tukey Kramer multiple comparisons test. ^aP < 0.05 vs control; ^bP < 0.05 vs FED; ^cP < 0.05 vs FENO; ^dP < 0.05 vs RES. FED: Fructose enriched diet; FENO: Fenofibrate; RES: Resveratrol; MDA: Malonaldehyde; GSH: Glutathione; SOD: Superoxide dismutase.