Hepatic phenotypes of HNF1B gene mutations: A case of neonatal cholestasis requiring portoenterostomy and literature review

Table 1 Laboratory data before and after portoenterostomy sec. Kasai that was performed at age 32 d

Age	Total bilirubin,μmol/L	Conjugated bilirubin,μmol/L	AST,μkat/L	ALT,μkat/L	GGT,μkat/L	ALP,μkat/L	Urea, mmol/L	Creatinine,μmol/L	Cholesterol, mmol/L	Albumin, g/L	INR	Mg, mmol/L
4 d	104	32	1.27	0.42	23.3	2.3	4.7	81	2.7	36.0	0.91	NA
27 d	145	100	1.57	0.92	10.2	7.2	2.2	29	3.7	36.8	1.05	NA
5 mo	135	110	2.59	2.24	6.8	8.1	5.2	22	9.5	42.0	0.84	NA
19 mo	30	25	3.15	3.09	7.5	11.4	5.3	18	6.7	42.7	0.95	0.90
2 yr	33	28	3.10	3.13	6.4	10.7	5.5	21	6.7	43.9	0.92	0.66

NA: Not available; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; GGT: γ-glutamyl transferase; ALP: Alkaline phosphatase; INR: International normalized ratio.