Impact of high glucose on metastasis of colon cancer cells

Figure 9 Effect of Stattic on matrix metalloproteinase-9 and signal transducer and activator of transcription 3 expression. In the HG30 group, the expression of both matrix metalloproteinase-9 (MMP-9) (A, B) and n-signal transducer and activator of transcription 3 (STAT3) (A, C) proteins were higher than in the C (control) group. When Stattic was added, the MMP-9/actin (B) and n-STAT3/actin (C) were significantly decreased. ^aP < 0.05 vs the control group; ^cP < 0.05 vs the 30 mmol/L glucose group. n = 6 per group. HG30: Glucose 30 mmol/L; Stattic: 1 × 10^-6 mol/L.