Retrospective Study
Copyright ©The Author(s) 2015.
World J Gastroenterol. Feb 21, 2015; 21(7): 2116-2123
Published online Feb 21, 2015. doi: 10.3748/wjg.v21.i7.2116
Table 4 Genotype at ABCC2 and parameters of proximal kidney tubular dysfunction and estimated glomerular filtration rate of 30 patients treated with adefovir dipivoxil n (%)
Genotype CC or CTGenotype TTP value
(n = 26)(n = 4)
Serum phosphate (mmol/L)0.86 ± 0.211.00 ± 0.25NS
TmP/GFR (mmol/L)0.73 ± 0.280.95 ± 0.42NS
Serum uric acid (umol/L)267.2 ± 120.3258.7 ± 26.4NS
FEUA (%)16.6 ± 14.69.5 ± 1.60.025
UBCR (mg/gCr)996.3 (68.2-14555.9)201.4 (81.5-497.7)0.038
Phosphate diabetes8 (30.8)1 (25.0)NS
Renal hypouricemia10 (38.5)0NS
β2-microglobulinuria14 (53.8)1 (25.0)NS
Nondiabetic glucosuria5 (19.2)0NS
Metabolic acidosis2 (7.7)0NS
eGFR (mL/min per 1.73 m2)62.8 ± 17.664.4 ± 2.1NS