Biological therapy in inflammatory bowel diseases: Access in Central and Eastern Europe

Table 2 Estimated number of newly diagnosed and prevalent Crohn's disease and ulcerative colitis patients aged ≥ 15 years in 9 selected Central and Eastern European countries, 2013

	Number of new patients			Total patient number
	CD	UC	Total	CD	UC	Total
Bulgaria	208	290	497	6162	11381	17543
Czech Republic	416	416	833	8768	16192	24960
Estonia	58	58	116	1090	2013	3103
Hungary	975	873	1848	9775	17897	27672
Latvia	57	80	137	1695	3131	4826
Lithuania	61	155	216	2482	4584	7066
Poland	1080	1506	2586	32049	59188	91237
Romania	287	405	692	16526	30520	47046
Slovakia	211	311	522	3687	6893	10580
Total	3353	4094	7447	82235	151798	234033

Data sources: Numbers of new patients were estimated based on incidence data by Burisch et al[8], 2014. In case of the Czech Republic mean of two available regional incidence data was calculated (4.65/10⁵ both for CD and UC), and for Bulgaria and Lithuania mean incidence rate of 8 CEE countries (Croatia, Czech Republic, Estonia, Hungary, Lithuania, Moldova, Romania, and Russia) calculated by Burisch et al[8] was applied (CD 3.3/10⁵, UC 4.6/10⁵). Total patient number was estimated using data from Gregus et al[12], 2014 for Slovakia (CD 80.5/10⁵, UC 150.5/10⁵) and Lakatos et al[10], 2011 for Hungary (CD 115.3/10⁵, UC 211.1/10⁵). For the other countries mean prevalence rates of Slovakia and Hungary were applied (CD 97.9/10⁵, UC 180.8/10⁵). Population data were obtained from Eurostat Statistics Database[34]. CD: Crohn's disease; UC: Ulcerative colitis.