MiR-21/RASA1 axis affects malignancy of colon cancer cells via RAS pathways

Figure 7 MiR-21 modulates apoptosis via RAS p21 GTPase activating protein 1 regulation. An annexin V-PE/7-AAD apoptosis detection kit was used to assess cell apoptosis in RKO cells in each group by flow cytometry. n = 3, ^aP < 0.05 vs pre-miR-21-LV; ^cP < 0.05 vs siRASA1. RASA1: RAS p21 GTPase activating protein 1; NC: Non-coding; LV: Lentivirus.