Association between hepatocellular carcinoma and tumor necrosis factor alpha polymorphisms in South Korea

Table 2 Baseline characteristics of study sample n (%)

Variable	Cases	Controls	P value1
n	157	201
Age (yr, mean ± SD)	56.00 ± 11.06	54.00 ± 11.22	0.061
Sex (male, %)	120 (76.4)	148 (73.6)	0.871
Hypertension	19 (12.1)	50 (24.9)	0.012
Diabetes mellitus	30 (19.1)	26 (12.9)	0.195
BMI > 25 kg/m2	40 (25.5)	51 (24.9)	1.000
Smoking	84 (53.5)	78 (38.8)	0.106
Drinking	90 (57.3)	93 (46.3)	0.274
Tumor size
< 5 cm	68 (43.3)	-	-
≥ 5 cm	89 (56.7)	-	-
Portal vein thrombosis
No	92 (58.6)	-	-
Yes	65 (41.4)	-	-
Surgical resection
No	145 (92.4)	-	-
Yes	12 (7.6)	-	-
CTx/RTx
No	27 (17.2)	-	-
Yes	130 (82.8)	-	-
TNM stage
I	34 (21.7)	-	-
II	37 (23.5)	-	-
III	51 (32.5)	-	-
IV	35 (22.3)	-	-
Okuda stage
I	46 (29.3)	-	-
II	68 (43.3)	-	-
III	43 (27.4)	-	-
CTP class
A	83 (52.9)	-	-
B	36 (22.9)	-	-
C	38 (24.2)	-	-

¹Derived from χ² tests for categorical data and Mann-Whitney tests for continuous data. BMI: Body mass index; CTx: Chemotherapy; RTx: Radiotherpay; CTP: Chlid-Turcotte-Pugh.