Transanal total mesorectal excision: Towards standardization of technique

Table 1 Types of studies and patient selection for transanal total mesorectal excision

Author, year	Type of study	No. of patients	Median age (yr)	Gender ratio (M:F)	Median BMI (kg/m²)	Neoadjuvant therapy	Median distance from AV/DL (cm)
Zorron, 2010	Prospective	9	63 (range, 52-81)	5:4	NR	4/9	AV 7.5 (range, 4-12)
Dumont, 2012	Prospective	4	67 (range, 70-66)	4:0	23 (range, 22-25)	NR	AV 5.3 (range, 4-7)
de Lacy, 2013	Prospective	20	65 ± 10.21 (range, 44-77)	11:9	25 ± 3.8 (range, 19-33)	14/20	DL 6.5 ± 3.31 (range, 2-15)
Lacy, 2013	Prospective	3	73 (range, 71-75)	1:2	22 (range, 16-25)	2/3	9.7 (range, 9-10)
Rouanet, 2013	Prospective	30	65 (range, 43-82)	30:0	26 (range, 21-32)	29/30	AV Low rectum (0-5 cm) 20/30; Middle rectum (5-10 cm) 10/30; Upper rectum (10-15 cm) 0/30
Sylla, 2013	Prospective	5	49 ± 9.81	3:2	26 ± 2.3	2/5	AV 5.7 (range, 4-10)
Atallah, 2014	Prospective	20	57 (range, 36-73)	14:6	24 (range 18-41)	17/20	AV 5 (range 1-9)
Chen, 2014	Prospective	20	58 ± 10.11	11:9	25 ± 3	11/20	AV 5.9 ± 1.7 (range, 2-8)
Chouillard, 2014	Prospective	16	58 (range, 34-81)	6:10	28 (range, 21-38)	Yes	NR
Fernandez-Hevia, 2014	Prospective Comparative	37	65 ± 11.81	24:13	24 ± 3.6 (range, 18-31)	27/37	AV Middle rectum 8.1 ± 1.71; Low rectum 3.5 cm ± 1.21
Kneist, 2014	Prospective	6	56 (range, 45-65)	5:1	25 (range, 23-28)	4/6	DL 1.7 (range, 0-3)
Meng, 2014	Prospective	3	80 (range, 76-82)	2:1	NR	1/3	AV 4.3 (range, 4-5)
Tuech, 2014	Prospective	56	65 (range, 39-83)	41:15	27 (range, 20-42)	47/56	AV 4 (range, 0-5)
Velthuis, 2014	Prospective Case-Matched	25	64 (range, 49-86)	18:7	25 (range, 20-36)	25/25	AV 8 (range, 0-16)
Wolthuis, 2014	Prospective	7	65 (range, 38-87)	6:1	25 (range, 17-32)	NR	NR
Atallah, 2015	Retrospective	4	45 (range, 26-59)	3:1	31 (range, 21-38)	3/4	AV 3.3 (range, 1-4)
Gomez Ruiz, 2015	Prospective	5	53 (range, 38-67)	4:1	26 (range, 22-31)	4/5	AV 5 (range, 4-6)
Knol, 2015	Prospective	10	61 (range 36-70)	8:2	27 (range 22-34)	10/10	DL 2.9 ± 1.21
Muratore, 2015	Prospective	26	66 (range, 38-84)	16:10	26 (range, 17-38)	19/26	4.4 (range, 3-6)
Prochazka, 2015	Prospective	17	68 (range, 49-81)	11:6	28 (range, 22-32)	12/17	AV 6 (range, 3-8)

¹Values reported as the mean ± SD. AV: Anal verge; DL: Dentate line; NR: Not reported; M: Male; F: Female; BMI: Body mass index.